Reliable manufacturers of Linezolid and its intermediates

Linezolid

Linezolid is an oxazolidinone, protein synthesis inhibitor: stop the growth and reproduction of bacteria by disrupting translation of messenger RNA (mRNA) into proteins in the ribosome.

Generic name: LINEZOLID
Brand name： ZYVOX
Therap-Cat: Antibiotic

Indications, Side Effects, Warnings Consumer Information of linezolid please refer to: www.drugs.com

Chemical information of Linezolid:

Chemical name：(s)-n-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide

CAS#: 165800-03-3

Chemical structure:

List of manufacturers approved for Generic Linezolid:
1. TEVA
2. WEST-WARD PHARMS
3. HOSPIRA
4. SANDOZ
5. MYLAN
6. GLENMARK
7. HETERO
8. AMNEAL
9. ALEMBIC
10. GATE PHARMS
11.FRESENIUS KABI
12. AUROBINDO
13. NOVEL LABS
14. NANG KUANG PHARM
15. ZYDUS PHARMS
16. SAGENT PHARMS
17. HQ SPCLT PHARMA

List of manufacturers applied DMF for Linezolid:
1. TEVA
2. GLENMARK
3. SYMED LABS
4. NEULAND

5. ALEMBIC
6. APOTEX
7. DR REDDYS

8. FORMOSA

9. RAKS PHARMA
10. UNION QUIMICO
11. USV PRIVATE
12. ZHEJIANG NEO DANKONG
13. JUBILANT
14. CADILA HEALTHCARE
15. AMOLI ORGANICS
16. LACAMAS
17. ZHEJIANG HISUN
18. MACLEODS

Manufacturers of Linezolid in China (data from www.sfda.gov.cn):

1. Shanghai Desano
2. CNPICL
3. Xiamen Encheng
4. Beijing Cell Technology
5. VenturePharma
6. Haimen Wisdom
7. Shanghai Shyndec Haimen
8. Henan Tailong
9. Hansoh Pharma (Lianyungang Hongchuang)
10. Beijing Winsunny Harmony(NHU Group)
11. Hubei Guangji
12. Zhejiang Huahai
13. Shandong Xinyi
14. Weihai Disu
15. Huazhong Pharma
......

Intermediates of Linezolid:

1. CAS# 168828-82-8 : (5R)-(hydroxymethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]oxazolidin-2-one
   chemical structure: 
2. CAS# 174649-09-3:
   (R) - (3 - (3- fluoro-4- morpholinophenyl) - 2- oxo-5-oxazolidinyl) methyl methanesulfonate
   
   
   

Reliable manufacturers of Linezolid intermediates:
1. Zhangjiakou Gerui
2. Zhejaing Neo-Dankong
3. Creative Organics
4. Perato Chem
5. Air Sea (Taizhou) 
......

* For detailed information or contact information of Linezolid manufacturers please leave message or send email to: michaelapci@gmail.com

ROS: Synthesis of Linezolid for reference:

Title:	Substd. oxazine and thiazine oxazolidinone antimicrobials
Authors:	Barbachyn, M.R.; Brickner, S.J.; Hutchinson, D.K. (Pharmacia Corp.)
Source:	EP 0717738; JP 1997502436; WO 9507271